Clinical trials in Nachod

53 clinical trials in Nachod, Czechia. Every trial is listed in the EU Clinical Trials Register and updated daily.

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53 trials in Nachod

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Chronic kidney disease

Recruiting

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug

Randomized Phase III trial of elecoglipron plus dapagliflozin on kidney outcomes and mortality in adults with chronic kidney disease

Registered drug

Czechia

Participants:18–64 years · 65+ years
Substances:AZD5004
Sponsor:AstraZeneca AB

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Psoriasis

Recruiting

Long-term safety study of deucravacitinib compared to ustekinumab in adults with moderate to severe plaque psoriasis

Registered drugNo placebo

Long-term safety study of deucravacitinib compared to ustekinumab in adults with moderate to severe plaque psoriasis

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Deucravacitinib
Sponsor:Bristol-Myers Squibb Services Unlimited Company

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Urinary incontinence+1

Recruiting

Orforglipron for stress urinary incontinence in women with obesity or overweight

Investigational

Orforglipron for stress urinary incontinence in women with obesity or overweight

Investigational

Czechia

Participants:18–64 years
Sponsor:Eli Lilly & Co.

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Chronic kidney disease+1

Recruiting

Study on the Effects of Baxdrostat and Dapagliflozin in Adults with Chronic Kidney Disease and High Blood Pressure

Registered drug

Study on the Effects of Baxdrostat and Dapagliflozin in Adults with Chronic Kidney Disease and High Blood Pressure

Registered drug

Czechia

Participants:18–64 years · 65+ years
Substances:Baxdrostat
Sponsor:AstraZeneca AB

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Neovascular age-related macular degeneration

Recruiting

Efficacy and safety of ABP 938 compared with aflibercept in participants with neovascular age‑related macular degeneration

InvestigationalNo placebo

Efficacy and safety of ABP 938 compared with aflibercept in participants with neovascular age‑related macular degeneration

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Aflibercept
Sponsor:Amgen Inc.

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Age-related macular degeneration

Recruiting

A Phase 2/3 Study of intravitreal mk-8748 versus aflibercept in adults with neovascular age‑related macular degeneration

Registered drugNo placebo

A Phase 2/3 Study of intravitreal mk-8748 versus aflibercept in adults with neovascular age‑related macular degeneration

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Aflibercept
Sponsor:Eyebiotech Limited

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Coagulation factor X level

Recruiting

VMX-C001 in Patients Taking Factor Xa Inhibitors Who Need Urgent Surgery or an Invasive Procedure With High Bleeding Risk

InvestigationalNo placebo

VMX-C001 in Patients Taking Factor Xa Inhibitors Who Need Urgent Surgery or an Invasive Procedure With High Bleeding Risk

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:VMX-C001
Sponsor:VarmX B.V.

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Obesity

Recruiting

RO7795068 for Weight Loss in Adults With Obesity or Overweight Without Type 2 Diabetes

Investigational

RO7795068 for Weight Loss in Adults With Obesity or Overweight Without Type 2 Diabetes

Investigational

Czechia

Participants:18–64 years · 65+ years
Sponsor:F. Hoffmann-La Roche AG

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Graves' disease

Recruiting

Long-Term Study of Imeroprubart in Adults With Graves' Disease

InvestigationalNo placebo

Long-Term Study of Imeroprubart in Adults With Graves' Disease

InvestigationalNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Imeroprubart
Sponsor:Immunovant Sciences GmbH

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Cardiac failure+1

Recruiting

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational

Study of Zenagamtide (NNC0487-0111) versus placebo in patients with heart failure with preserved or mildly reduced ejection fraction and obesity

Investigational

Czechia

Participants:18–64 years · 65+ years
Sponsor:Novo Nordisk A/S

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Dermatitis atopic

Recruiting

Phase 2b Randomized Double‑Blind Study of Oral PF‑08049820 in Adults with Moderate to Severe Atopic Dermatitis

Investigational

Phase 2b Randomized Double‑Blind Study of Oral PF‑08049820 in Adults with Moderate to Severe Atopic Dermatitis

Investigational

Czechia

Participants:18–64 years
Sponsor:Pfizer Inc.

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Diabetic retinal oedema

Recruiting

A study to compare the efficacy and safety of AVT29 and aflibercept in patients with diabetic macular edema

Registered drugNo placebo

A study to compare the efficacy and safety of AVT29 and aflibercept in patients with diabetic macular edema

Registered drugNo placebo

Czechia

Participants:18–64 years · 65+ years
Substances:Aflibercept
Sponsor:Alvotech Swiss AG

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Clinical research in Nachod

What the registry says about research in the country

01 Metabolic & Cardiovascular Research

Clinical trials focusing on hypertriglyceridemia and cardiovascular health, evaluating innovative treatments for managing lipid levels and preventing adverse cardiovascular events.

Severe Hypertriglyceridemia Treatment
Cardiovascular Disease Prevention
Type 2 Diabetes Management

Multiple studies are testing new compounds like plozasiran and olezarsen for triglyceride reduction.

02 Dermatological Studies

Comprehensive research into chronic skin conditions, with emphasis on plaque psoriasis and atopic dermatitis treatments.

Moderate to Severe Psoriasis
Atopic Dermatitis
Alopecia Areata

Studies evaluate long-term safety and efficacy of novel therapeutic agents for persistent skin conditions.

03 Chronic Disease Management

Investigations into treatments for chronic kidney disease and heart failure, with particular focus on combination therapies.

Heart Failure with Reduced Ejection Fraction
CKD with Hypertension
Obesity Management

Research includes innovative approaches to managing complex chronic conditions and their complications.

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